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Botanical Name :Adhatoda vasica, Justicia adhatoda
Sanskrit name : Vasaka
English Name : Malabar nut
Family : Acanthaceae
Plant Parts Used : Leaves
Description of
Adhatoda vasica:
It is a small evergreen, subherbacious bush. The Leaves are 10 to 16 cms in length, minutely pubescent and broadly lanceolate. The inflorescence is dense, short pedunculate, bractate and spike terminal. The corolla is large and white with lower lip streaked purple. The fruit is a 4-seeded small capsule.
It is a small evergreen, subherbacious bush. The Leaves are 10 to 16 cms in length, minutely pubescent and broadly lanceolate. The inflorescence is dense, short pedunculate, bractate and spike terminal. The corolla is large and white with lower lip streaked purple. The fruit is a 4-seeded small capsule.
Traditional
uses:
The plant is recommended for a variety of ailments such as bronchitis, asthma, fever, jaundice etc. The leaves & roots are efficacious in coughs, arthritis, diarrhoea & dysentery and have the best haemostatic quality. Leaves are anti-inflammatory, analgesic, effective in skin disorders, cardiotonic. This is one of the most potent anti tuberculosis drug. Vasicine is also reported for its anthelmintic and weak hypotensive activity.
The plant is recommended for a variety of ailments such as bronchitis, asthma, fever, jaundice etc. The leaves & roots are efficacious in coughs, arthritis, diarrhoea & dysentery and have the best haemostatic quality. Leaves are anti-inflammatory, analgesic, effective in skin disorders, cardiotonic. This is one of the most potent anti tuberculosis drug. Vasicine is also reported for its anthelmintic and weak hypotensive activity.
Phytochemistry:
The major bioactive constituent of Adhatoda vasica is a pyrralazoquinoline alkaloid – vasicine. The other alkaloids include vasicol, adhatonine, vasicinone, vasicinol, vasicinolone etc. The other constituents include aliphatic hydroketones viz., 37-hydroxyhexateracont-1-en-15-one and 37-hydroxy hentetracontan-19-one; common phytosterols viz., a-sitosterol and its D-glucose.
The major bioactive constituent of Adhatoda vasica is a pyrralazoquinoline alkaloid – vasicine. The other alkaloids include vasicol, adhatonine, vasicinone, vasicinol, vasicinolone etc. The other constituents include aliphatic hydroketones viz., 37-hydroxyhexateracont-1-en-15-one and 37-hydroxy hentetracontan-19-one; common phytosterols viz., a-sitosterol and its D-glucose.
Pharmacology:
Adhatoda vasica has been evaluated for various pharmacological activities. Adhatoda vasica has been found to be potent bronchodilator and expectorant. Adhatoda vasica is also reported to have abortifacient, uterotonic, antimycobaterial, wound healing, hypotensive, myocardial depressant and hypoglycemic activity.
Adhatoda vasica is used for :
Bleeding Disorders :
• bleeding due to idiopathic (unknown) thrombocytopenic (blood does not have enough platelets) purpura (excessive bruising)
Cardiovascular Conditions
• moderate hypotensive activity (lowers blood pressure
• pulmonary diseases
Female Diseases
• assists uterine involution (rolling or turning inward)
• menorrhagia (excessive menstrual bleeding)
• Postpartum (after childbrith) hemorrhage
• uterine stimulant activity
Gastrointestinal Conditions
• dyspepsia
• local bleeding due to peptic ulcer and/or piles
Respiratory Tract Conditions
• acute and chronic bronchitis often combined with the herbs Licorice and Marshmallow for soothing the respiratory tract
• allergic asthma, often combined with the herbs Tylophora, etc.
• antihistamine effects (the leaves may be dried and smoked to relieve asthma)
• broncho-dilation effects
• emphysema
• obstructive airway disease (chronic)
• phthisis (wasting of the ssues as in tuberculosis)
• relieves cough and breathlessness
Other Conditions
• Bleeding gums (applied locally) • Diphtheria • pyorrhea, a gum disease (applied locally) • Fever • Tuberculosis • Typhus fever
Toxicology Caution :
• The leaf extract, is considered safe and the oil has low toxicity
• Contraindicated in pregnancy except at birth. Large doses can cause Diarrhoea, Vomiting, Irritation of the alimentary canal
Dosage :
• 1-3 g/day of dried leaves.
• 0.5-1.5 g/day dried root
Adhatoda vasica has been evaluated for various pharmacological activities. Adhatoda vasica has been found to be potent bronchodilator and expectorant. Adhatoda vasica is also reported to have abortifacient, uterotonic, antimycobaterial, wound healing, hypotensive, myocardial depressant and hypoglycemic activity.
Adhatoda vasica is used for :
Bleeding Disorders :
• bleeding due to idiopathic (unknown) thrombocytopenic (blood does not have enough platelets) purpura (excessive bruising)
Cardiovascular Conditions
• moderate hypotensive activity (lowers blood pressure
• pulmonary diseases
Female Diseases
• assists uterine involution (rolling or turning inward)
• menorrhagia (excessive menstrual bleeding)
• Postpartum (after childbrith) hemorrhage
• uterine stimulant activity
Gastrointestinal Conditions
• dyspepsia
• local bleeding due to peptic ulcer and/or piles
Respiratory Tract Conditions
• acute and chronic bronchitis often combined with the herbs Licorice and Marshmallow for soothing the respiratory tract
• allergic asthma, often combined with the herbs Tylophora, etc.
• antihistamine effects (the leaves may be dried and smoked to relieve asthma)
• broncho-dilation effects
• emphysema
• obstructive airway disease (chronic)
• phthisis (wasting of the ssues as in tuberculosis)
• relieves cough and breathlessness
Other Conditions
• Bleeding gums (applied locally) • Diphtheria • pyorrhea, a gum disease (applied locally) • Fever • Tuberculosis • Typhus fever
Toxicology Caution :
• The leaf extract, is considered safe and the oil has low toxicity
• Contraindicated in pregnancy except at birth. Large doses can cause Diarrhoea, Vomiting, Irritation of the alimentary canal
Dosage :
• 1-3 g/day of dried leaves.
• 0.5-1.5 g/day dried root
Marker constituents:
Vasicine & Vasicinone.
Vasicine & Vasicinone.
Main uses:
Bronchodilator, expectorant, uterotonic.
Bronchodilator, expectorant, uterotonic.
ADHATODA
VASICA ( VASAKA, MALABAR NUT, ADULSA )
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PRODUCT CODE: | NE/ AV/ 008 |
DESCRIPTION
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LIGHT
BROWN COLOURED POWDER WITH SLIGHTLY BITTER TASTE
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IDENTIFICATION
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ALKALOIDS
BY T. L. C.
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SOLUBILITY
IN WATER IN 50% V/V ALCOHOL |
80% MIN. 80% MIN. |
ASSAY ALKALOIDS | 0.5% MIN. |
*Disclaimer
"These statements have not been evaluated by the food and drug administration or any other regulatory body. These products are not intended to diagnose, treat, cure, or prevent any
disease.
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